Sound waves could help chemo reach breast tumors

NCT ID NCT07616440

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This pilot study tests whether focused ultrasound, combined with tiny gas bubbles (microbubbles), can help chemotherapy drugs penetrate deeper into HER2-positive breast tumors. Twenty women will receive the ultrasound treatment alongside standard neoadjuvant therapy before surgery. The goal is to see if this approach is safe and leads to higher rates of complete tumor disappearance compared to historical data.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

SonoVue® ultrasound contrast agent microbubbles

What this could lead to

If it works, this could improve how well chemotherapy reaches tumors, potentially increasing the chance of complete tumor disappearance before surgery.

What could go wrong

This is a very small pilot study (20 people) with no control group, so results may not be reliable. The procedure involves repeated ultrasound sessions and injections, which may cause discomfort or unknown side effects.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

HER2 positive breast carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • The Second Affiliated Hospital Zhejiang University School of Medicine (SAHZU)

    RECRUITING

    Hangzhou, Zhejiang, 310000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••