Sound waves could help chemo reach breast tumors
NCT ID NCT07616440
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times
Summary
This pilot study tests whether focused ultrasound, combined with tiny gas bubbles (microbubbles), can help chemotherapy drugs penetrate deeper into HER2-positive breast tumors. Twenty women will receive the ultrasound treatment alongside standard neoadjuvant therapy before surgery. The goal is to see if this approach is safe and leads to higher rates of complete tumor disappearance compared to historical data.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- SonoVue® ultrasound contrast agent microbubbles
- What this could lead to
- If it works, this could improve how well chemotherapy reaches tumors, potentially increasing the chance of complete tumor disappearance before surgery.
- What could go wrong
- This is a very small pilot study (20 people) with no control group, so results may not be reliable. The procedure involves repeated ultrasound sessions and injections, which may cause discomfort or unknown side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
The Second Affiliated Hospital Zhejiang University School of Medicine (SAHZU)
RECRUITINGHangzhou, Zhejiang, 310000, China
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a triple drug combo shrink HER2-Positive breast tumors before surgery?
- Can an extra radiation dose keep HER2+ breast cancer at bay?
- Can a drug cocktail cure metastatic breast cancer? a trial aims to find out
- Can less chemo be enough? a trial challenges standard treatment for HER2-Positive breast cancer
- Can a new drug outsmart resistant breast cancer?
- Can a new targeted drug outperform the current standard for HER2-Positive breast cancer?