Sound waves may unlock Brain's barrier to fight tumors
NCT ID NCT05733312
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study uses focused ultrasound to temporarily open the blood-brain barrier during brain tumor surgery. Researchers will place tiny catheters to sample fluid from different brain areas to see how the barrier affects the tumor environment. Only 6 adults with large brain tumors will take part, and the goal is to gather information, not to treat the tumor.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
focused ultrasound (ExAblate Neuro device)
What this could lead to
If successful, this could reveal how the blood-brain barrier affects drug delivery to brain tumors, potentially guiding future treatments.
What could go wrong
This is a very small, early-stage study (6 people) focused on measurement, not treatment. It may not lead to direct benefits for participants.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic Minnesota
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact