Foam injection may ease pain from polycystic kidney and liver cysts

NCT ID NCT04111692

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study looks at whether foam sclerotherapy can reduce pain and improve quality of life for people with autosomal dominant polycystic kidney or liver disease who have large, painful cysts. Researchers will treat 100 adults with 1-3 dominant cysts and follow them for 12 months. The goal is to see if the procedure shrinks cysts and eases symptoms.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

Active substance
foam sclerotherapy
What this could lead to
If it works, this could offer a minimally invasive way to reduce cyst-related pain and improve daily life for people with polycystic kidney or liver disease.
What could go wrong
This is an early observational study with only 100 participants, so results may not apply to everyone. The procedure carries risks like infection, bleeding, or cyst recurrence.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mayo Clinic

    RECRUITING

    Rochester, Minnesota, 55905, United States

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