Could a poop transplant cure your constipation?

NCT ID NCT07386795

Not yet recruiting Disease control Sponsor: Peking Union Medical College Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether transplanting healthy gut bacteria (fecal microbiota transplant, or FMT) combined with prebiotics can relieve chronic constipation. Nineteen adults with hard-to-treat constipation will receive the treatment via colonoscopy. The goal is to improve bowel movements and gut health, with researchers monitoring safety and changes in the microbiome.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fecal microbiota transplant (FMT) combined with prebiotics
What this could lead to: If successful, this approach could offer a new, safer treatment option for people with chronic constipation that doesn't respond to standard therapies.
What could go wrong: This is a very small, early-stage trial with only 19 participants and no comparison group, so results may not apply widely. Side effects like bloating, diarrhea, or rare infections are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

constipation disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CHRONIC CONSTIPATION CONSTIPATION - FUNCTIONAL FECAL MICROBIOTA TRANSPLANTATION

Contacts and locations

Locations

Peking Union Medical College Hospital

Beijing, China

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