New drug targets 'Undruggable' cancer mutation in early human trial
NCT ID NCT06244771
Summary
This study is testing a new drug called FMC-376 for people with advanced solid tumors that have a specific genetic change called KRAS G12C. The main goals are to find a safe and effective dose and to see if the drug can shrink or control tumors. It is for patients whose cancer has grown despite standard treatments, including those with lung, colorectal, or pancreatic cancer.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Community Clinical Trials
COMPLETEDKingwood, Texas, 77339, United States
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Eastern Health - Box Hill Hospital
RECRUITINGBox Hill, Victoria, 3128, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Florida Cancer Specialists and Research Institute
COMPLETEDLake Mary, Florida, 32746, United States
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GenesisCare North Adelaide
RECRUITINGNorth Adelaide, South Australia, 5006, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Icon Cancer Centre Kurralta Park
RECRUITINGKurralta Park, South Australia, 5037, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Karmanos Cancer Institute
RECRUITINGDetroit, Michigan, 48201, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Korea University Anam Hospital
RECRUITINGSeoul, Seongbuk-gu, 02841, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Linear Clinical Research Ltd
RECRUITINGNedlands, Western Australia, 6009, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Macquarie University
RECRUITINGMacquarie Park, New South Wales, 2109, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Northwest Cancer Centers
RECRUITINGDyer, Indiana, 46311, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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START Mountain Region
RECRUITINGWest Valley City, Utah, 84119, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Seoul National University Bundang Hospital
RECRUITINGGyeonggi-do, Seongnam-si, 13620, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Seoul National University Hospital
NOT_YET_RECRUITINGSeoul, Jongno-gu, 03080, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Severance Hospital
NOT_YET_RECRUITINGSeoul, Seodaemun-gu, 03722, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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South Texas Accelerated Research Therapeutics, LLC
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Tasman Health Care
RECRUITINGSouthport, Queensland, 4215, Australia
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Catholic University of Korea, St. Vincent's Hospital
RECRUITINGGyeonggi-do, Suwon-si, 16247, South Korea
Contact Phone: •••-•••-••••
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The University of Kansas Cancer Center
RECRUITINGFairway, Kansas, 66205, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The University of Texas MD Anderson Cancer Center
RECRUITINGHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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UT Health San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California Irvine (UCI) - Chao Family Comprehensive Cancer Center
COMPLETEDOrange, California, 92868, United States
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University of California San Diego (UC San Diego) Health - Jacobs Medical Center - Moores Cancer Center
RECRUITINGLa Jolla, California, 92037, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of California San Francisco (UCSF) - Helen Diller Family Comprehensive Cancer Center
RECRUITINGSan Francisco, California, 94158, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Pennsylvania
RECRUITINGPhiladelphia, Pennsylvania, 19104, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Virginia Cancer Specialists
RECRUITINGFairfax, Virginia, 22031, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
Explore the condition pages connected to this study.