New pill combo could replace chemo for some advanced breast cancers

NCT ID NCT07371910

First seen Jan 29, 2026 · Last updated May 16, 2026 · Updated 14 times

Summary

This study tests a new approach for people with a specific genetic type of advanced breast cancer (HRD-positive, HER2-negative). After initial chemotherapy, one group switches to a daily pill combination (fluorizoparib + apatinib) for long-term control, while the other group stays on standard chemo. The goal is to see if the pill combo keeps the cancer from growing longer than chemo. About 200 women aged 18-70 are taking part.

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Contacts and locations

Locations

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, 510030, China

Conditions

Explore the condition pages connected to this study.