New pill combo could delay advanced breast cancer progression

NCT ID NCT07371910

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study tests whether a combination of two targeted pills (fluorizoparib and apatinib) works better than standard chemotherapy for people with a specific genetic type of advanced breast cancer (HRD-positive, HER2-negative). About 200 participants will be randomly assigned to either the pill combo or continued chemo. The goal is to see if the pills can delay cancer growth with fewer side effects.

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Conditions

The condition(s) this trial relates to.

breast carcinoma breast neoplasm Her2-receptor negative breast cancer hormone receptor-positive breast cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sun Yat-sen Memorial Hospital, Sun Yat-sen University

    Guangzhou, Guangdong, 510030, China