Waking up the brain: new drug may prevent Post-Surgery confusion

NCT ID NCT07277881

Not yet recruiting Symptom relief Sponsor: Medical University of Gdansk Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether giving flumazenil after hip replacement surgery can reverse the effects of the sedative remimazolam and improve thinking. 150 adults will receive either flumazenil or a placebo right after surgery. Researchers will check their memory and confusion levels over the next two days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: flumazenil
What this could lead to: If it works, this could point toward a simple way to prevent confusion and memory problems after hip replacement surgery.
What could go wrong: This is a small, early-phase trial. The benefit may be small or not appear at all, and flumazenil can cause side effects like anxiety or rapid heart rate.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for HIP ARTHROPLASTY, TOTAL are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Emergence Delirium

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HIP ARTHROPLASTY, TOTAL POSTOPERATIVE DELIRIUM REMIMAZOLAM SEDATION

More trials for these conditions

Other studies related to the condition(s) this trial covers.