Does a potent steroid cream cause fluid retention? new study investigates
NCT ID NCT02360202
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study measured fluid retention in 30 people with bullous pemphigoid who were treated with a strong steroid cream (clobetasol propionate). Researchers used bioimpedance to track changes in body water over 30 days. The goal was to understand if the cream causes fluid buildup and whether dietary changes like salt restriction might be helpful.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- clobetasol propionate cream
- What this could lead to
- If successful, this could clarify whether a salt-free diet is needed during treatment with strong topical steroids for bullous pemphigoid.
- What could go wrong
- This is a small, completed Phase 4 study with only 30 participants, so results may not apply broadly. It measures fluid changes, not treatment effectiveness or safety.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Rouen University Hospital
Rouen, 76031, France
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