Does a potent steroid cream cause fluid retention? new study investigates
NCT ID NCT02360202
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study measured fluid retention in 30 people with bullous pemphigoid who were treated with a strong steroid cream (clobetasol propionate). Researchers used bioimpedance to track changes in body water over 30 days. The goal was to understand if the cream causes fluid buildup and whether dietary changes like salt restriction might be helpful.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
clobetasol propionate cream
What this could lead to
If successful, this could clarify whether a salt-free diet is needed during treatment with strong topical steroids for bullous pemphigoid.
What could go wrong
This is a small, completed Phase 4 study with only 30 participants, so results may not apply broadly. It measures fluid changes, not treatment effectiveness or safety.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Rouen University Hospital
Rouen, 76031, France