Could a common steroid help brain bleed survivors walk again?
NCT ID NCT06409364
First seen Nov 01, 2025 · Last updated Jun 22, 2026 · Updated 32 times
Summary
This study tests whether a steroid pill called fludrocortisone can reduce death and disability in people who have had a brain bleed from a burst aneurysm. The trial will enroll 524 critically ill adults who have had their aneurysm secured. Half will receive the drug, half a placebo, and researchers will measure how independent they are six months later.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
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Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Auckland City Hospital
NOT_YET_RECRUITINGAuckland, 1023, New Zealand
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Gold Coast University Hospital
RECRUITINGGold Coast, Queensland, 4215, Australia
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John Hunter Hospital
NOT_YET_RECRUITINGNew Lambton Heights, New South Wales, 2042, Australia
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Monash Medical Centre
NOT_YET_RECRUITINGClayton, Victoria, 3168, Australia
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Nepean Hospital
RECRUITINGPenrith, New South Wales, 2747, Australia
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Prince of Wales Hospital
NOT_YET_RECRUITINGRandwick, New South Wales, 2031, Australia
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Princess Alexandra Hospital
NOT_YET_RECRUITINGWoolloongabba, Queensland, 4102, Australia
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Royal Brisbane Women's Hospital
NOT_YET_RECRUITINGBrisbane, Queensland, 4029, Australia
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Royal Hobart Hospital
NOT_YET_RECRUITINGHobart, Tasmania, 7000, Australia
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Royal North Shore Hospital
NOT_YET_RECRUITINGSt Leonards, New South Wales, 2065, Australia
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St Vincent's Hospital (Melbourne)
NOT_YET_RECRUITINGFitzroy, Victoria, 3065, Australia
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The Alfred Hospital
NOT_YET_RECRUITINGMelbourne, Victoria, 3044, Australia
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Townsville Hospital
NOT_YET_RECRUITINGTownsville, Queensland, 4814, Australia
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Wellington Hospital
NOT_YET_RECRUITINGWellington, 6011, New Zealand
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Westmead Hospital
NOT_YET_RECRUITINGWestmead, New South Wales, 2145, Australia
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Wollongong Hospital
NOT_YET_RECRUITINGWollongong, New South Wales, 2521, Australia
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fludrocortisone (a steroid hormone pill)
What this could lead to
If it works, this could offer a simple, cheap treatment to improve recovery and reduce long-term disability after a brain bleed from a burst aneurysm.
What could go wrong
This is a mid-stage trial, so results are not guaranteed. The drug may not improve outcomes, and steroids can have side effects like infection or electrolyte imbalance.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.