Could a common steroid help brain bleed survivors walk again?

NCT ID NCT06409364

Recruiting now Disease control Sponsor: The George Institute Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a steroid pill called fludrocortisone can reduce death and disability in people who have had a brain bleed from a burst aneurysm. The trial will enroll 524 critically ill adults who have had their aneurysm secured. Half will receive the drug, half a placebo, and researchers will measure how independent they are six months later.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: fludrocortisone (a steroid hormone pill)
What this could lead to: If it works, this could offer a simple, cheap treatment to improve recovery and reduce long-term disability after a brain bleed from a burst aneurysm.
What could go wrong: This is a mid-stage trial, so results are not guaranteed. The drug may not improve outcomes, and steroids can have side effects like infection or electrolyte imbalance.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acquired aneurysmal subarachnoid hemorrhage subarachnoid hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ANEURYSMAL SUBARACHNOID HEMORRHAGE

Contacts and locations

Locations

Auckland City Hospital
NOT_YET_RECRUITING

Auckland, 1023, New Zealand
Gold Coast University Hospital
RECRUITING

Gold Coast, Queensland, 4215, Australia
John Hunter Hospital
NOT_YET_RECRUITING

New Lambton Heights, New South Wales, 2042, Australia
Monash Medical Centre
NOT_YET_RECRUITING

Clayton, Victoria, 3168, Australia
Nepean Hospital
RECRUITING

Penrith, New South Wales, 2747, Australia
Prince of Wales Hospital
NOT_YET_RECRUITING

Randwick, New South Wales, 2031, Australia
Princess Alexandra Hospital
NOT_YET_RECRUITING

Woolloongabba, Queensland, 4102, Australia
Royal Brisbane Women's Hospital
NOT_YET_RECRUITING

Brisbane, Queensland, 4029, Australia
Royal Hobart Hospital
NOT_YET_RECRUITING

Hobart, Tasmania, 7000, Australia
Royal North Shore Hospital
NOT_YET_RECRUITING

St Leonards, New South Wales, 2065, Australia
St Vincent's Hospital (Melbourne)
NOT_YET_RECRUITING

Fitzroy, Victoria, 3065, Australia
The Alfred Hospital
NOT_YET_RECRUITING

Melbourne, Victoria, 3044, Australia
Townsville Hospital
NOT_YET_RECRUITING

Townsville, Queensland, 4814, Australia
Wellington Hospital
NOT_YET_RECRUITING

Wellington, 6011, New Zealand
Westmead Hospital
NOT_YET_RECRUITING

Westmead, New South Wales, 2145, Australia
Wollongong Hospital
NOT_YET_RECRUITING

Wollongong, New South Wales, 2521, Australia

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