New flu vaccine shows promise for teens and adults

NCT ID NCT05513053

Completed ⭐️ VACCINE ⭐️ Sponsor: Sanofi Pasteur, a Sanofi Company Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a recombinant flu vaccine (RIV4) in over 1,300 people aged 9 to 49. The goal was to see if the immune response in children and teens (9-17) was as good as in adults (18-49). Researchers measured antibody levels before and 29 days after vaccination. The trial also monitored safety for all participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Quadrivalent recombinant influenza vaccine (RIV4), also known as Supemtek or Flublok Quadrivalent
What this could lead to: If successful, this could confirm that the recombinant flu vaccine works as well in teens as in adults, offering a safe option for younger age groups.
What could go wrong: This is a completed phase 3 trial, but results only show immune response and short-term safety. Long-term protection and real-world effectiveness are not yet proven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

INFLUENZA IMMUNIZATION

Contacts and locations

Locations

AMR - Newton Site Number : 8400021

Newton, Kansas, 67114, United States
Alabama Clinical Therapeutics North Tower Site Number : 8400024

Birmingham, Alabama, 35205, United States
Benchmark Research - Austin Site Number : 8400004

Austin, Texas, 78705, United States
Birmingham Pediatric Associates Site Number : 8400023

Birmingham, Alabama, 35205, United States
California Research Foundation Site Number : 8400003

San Diego, California, 92123-1881, United States
Coastal Carolina Research Center - N Charleston Site Number : 8400022

North Charleston, South Carolina, 29405, United States
Coastal Pediatric Research Charleston Site Number : 8400005

Charleston, South Carolina, 29414, United States
Investigational Site Number : 2030001

Jindřichův Hradec, 37701, Czechia
Investigational Site Number : 6160003

Bydgoszcz, 85-796, Poland
Investigational Site Number : 6160004

PuÅ'awy, Lubusz Voivodeship, 24-100, Poland
Investigational Site Number : 6160005

Siemianowice Śląskie, Silesian Voivodeship, 41-103, Poland
Investigational Site Number : 6160006

Tarnów, 33-100, Poland
Investigational Site Number : 6160007

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-079, Poland
Investigational Site Number : 6160008

Warsaw, 02-637, Poland
Investigational Site Number : 6160010

Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-048, Poland
Investigational Site Number : 6160012

Wroclaw, 53-149, Poland
Investigational Site Number : 7240001

Móstoles, 28938, Spain
Investigational Site Number : 7240005

Málaga, 29015, Spain
Investigational Site Number : 7240006

Centelles, Barcelona [Barcelona], 08540, Spain
Investigational Site Number : 7240007

Seville, 41014, Spain
Investigational Site Number : 7240018

Madrid, 28660, Spain
J. Lewis Research Site Number : 8400017

Salt Lake City, Utah, 84109, United States
JBR Clinical Research Site Number : 8400001

Salt Lake City, Utah, 84107, United States
Kentucky Pediatics / Adult Research Site Number : 8400010

Bardstown, Kentucky, 40004, United States
Meridian Clinical Research Norfolk Site Number : 8400011

Norfolk, Nebraska, 68701, United States
Meridian Clinical Research Site Number : 8400006

Binghamton, New York, 13905, United States
Meridian Clinical Research- Sioux City Site Number : 8400007

Sioux City, Iowa, 51106, United States
Ohio Pediatric Research Site Number : 8400020

Dayton, Ohio, 45414, United States
Rainbow Pediatrics Site Number : 8400014

Barnwell, South Carolina, 29812, United States
The Children's Clinic Of Jonesboro PA Site Number : 8400025

Jonesboro, Arkansas, 72401, United States
Velocity Clinical Research Lincoln Site Number : 8400013

Lincoln, Nebraska, 68510, United States
Velocity Clinical Research Portsmouth Site Number : 8400015

Portsmouth, Virginia, 23703, United States
Velocity Clinical Research Site Number : 8400012

New Orleans, Louisiana, 70119, United States
Velocity Clinical Research Vestal Site Number : 8400016

Vestal, New York, 13850, United States
Velocity Clinical Research, Omaha Site Number : 8400009

Omaha, Nebraska, 68134, United States

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