New flu vaccine shows promise for teens and adults

NCT ID NCT05513053

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tested a recombinant flu vaccine (RIV4) in over 1,300 people aged 9 to 49. The goal was to see if the immune response in children and teens (9-17) was as good as in adults (18-49). Researchers measured antibody levels before and 29 days after vaccination. The trial also monitored safety for all participants.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Quadrivalent recombinant influenza vaccine (RIV4), also known as Supemtek or Flublok Quadrivalent

What this could lead to

If successful, this could confirm that the recombinant flu vaccine works as well in teens as in adults, offering a safe option for younger age groups.

What could go wrong

This is a completed phase 3 trial, but results only show immune response and short-term safety. Long-term protection and real-world effectiveness are not yet proven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

influenza prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AMR - Newton Site Number : 8400021

    Newton, Kansas, 67114, United States

  • Alabama Clinical Therapeutics North Tower Site Number : 8400024

    Birmingham, Alabama, 35205, United States

  • Benchmark Research - Austin Site Number : 8400004

    Austin, Texas, 78705, United States

  • Birmingham Pediatric Associates Site Number : 8400023

    Birmingham, Alabama, 35205, United States

  • California Research Foundation Site Number : 8400003

    San Diego, California, 92123-1881, United States

  • Coastal Carolina Research Center - N Charleston Site Number : 8400022

    North Charleston, South Carolina, 29405, United States

  • Coastal Pediatric Research Charleston Site Number : 8400005

    Charleston, South Carolina, 29414, United States

  • Investigational Site Number : 2030001

    Jindřichův Hradec, 37701, Czechia

  • Investigational Site Number : 6160003

    Bydgoszcz, 85-796, Poland

  • Investigational Site Number : 6160004

    PuÅ'awy, Lubusz Voivodeship, 24-100, Poland

  • Investigational Site Number : 6160005

    Siemianowice Śląskie, Silesian Voivodeship, 41-103, Poland

  • Investigational Site Number : 6160006

    Tarnów, 33-100, Poland

  • Investigational Site Number : 6160007

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-079, Poland

  • Investigational Site Number : 6160008

    Warsaw, 02-637, Poland

  • Investigational Site Number : 6160010

    Bydgoszcz, Kuyavian-Pomeranian Voivodeship, 85-048, Poland

  • Investigational Site Number : 6160012

    Wroclaw, 53-149, Poland

  • Investigational Site Number : 7240001

    Móstoles, 28938, Spain

  • Investigational Site Number : 7240005

    Málaga, 29015, Spain

  • Investigational Site Number : 7240006

    Centelles, Barcelona [Barcelona], 08540, Spain

  • Investigational Site Number : 7240007

    Seville, 41014, Spain

  • Investigational Site Number : 7240018

    Madrid, 28660, Spain

  • J. Lewis Research Site Number : 8400017

    Salt Lake City, Utah, 84109, United States

  • JBR Clinical Research Site Number : 8400001

    Salt Lake City, Utah, 84107, United States

  • Kentucky Pediatics / Adult Research Site Number : 8400010

    Bardstown, Kentucky, 40004, United States

  • Meridian Clinical Research Norfolk Site Number : 8400011

    Norfolk, Nebraska, 68701, United States

  • Meridian Clinical Research Site Number : 8400006

    Binghamton, New York, 13905, United States

  • Meridian Clinical Research- Sioux City Site Number : 8400007

    Sioux City, Iowa, 51106, United States

  • Ohio Pediatric Research Site Number : 8400020

    Dayton, Ohio, 45414, United States

  • Rainbow Pediatrics Site Number : 8400014

    Barnwell, South Carolina, 29812, United States

  • The Children's Clinic Of Jonesboro PA Site Number : 8400025

    Jonesboro, Arkansas, 72401, United States

  • Velocity Clinical Research Lincoln Site Number : 8400013

    Lincoln, Nebraska, 68510, United States

  • Velocity Clinical Research Portsmouth Site Number : 8400015

    Portsmouth, Virginia, 23703, United States

  • Velocity Clinical Research Site Number : 8400012

    New Orleans, Louisiana, 70119, United States

  • Velocity Clinical Research Vestal Site Number : 8400016

    Vestal, New York, 13850, United States

  • Velocity Clinical Research, Omaha Site Number : 8400009

    Omaha, Nebraska, 68134, United States