Flu vaccine injected into tumors: a new weapon against skin cancer?
NCT ID NCT06664151
First seen Nov 01, 2025 · Last updated Jun 20, 2026 · Updated 28 times
Summary
This early-phase trial is testing whether injecting the seasonal flu vaccine directly into skin cancer tumors can boost the immune system's attack on the cancer. About 25 adults with a type of skin cancer called cutaneous squamous cell carcinoma will receive one injection into their tumor before standard surgery. The main goal is to measure changes in immune cells within the tumor, not to treat the cancer itself.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Dana-Farber Cancer Institute
RECRUITINGBoston, Massachusetts, 02215, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Fluzone Trivalent (influenza vaccine, flu shot)
What this could lead to
If it works, this could point toward a new way to use existing vaccines to help the immune system fight skin cancer.
What could go wrong
This is a very early, small trial (25 people) focused on immune cell changes, not on curing cancer. It may not lead to any treatment benefit.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.