New study finds best way to treat hemorrhoids without surgery

NCT ID NCT05089500

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looked at two common treatments for grade I-III internal hemorrhoids: injection sclerotherapy and rubber band ligation. Researchers followed 984 patients across multiple hospitals to see which treatment worked better and had fewer side effects. The goal is to help doctors choose the best option for each patient.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

sclerosing agent (polidocanol)

What this could lead to

If successful, this could help doctors choose the best minimally invasive treatment for internal hemorrhoids, reducing recurrence and complications.

What could go wrong

This is a completed study comparing existing treatments, so no major breakthroughs are expected. Results may not apply to severe hemorrhoids or other types.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hemorrhoid internal hemorrhoid

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Mingkai Chen

    Wuhan, Hubei, 430060, China

  • Renmin Hospital of Wuhan University

    Wuhan, Hubei, 430060, China