Fish oil fails to deliver in nerve damage trial
NCT ID NCT05145452
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether high-dose fish oil supplements could improve nerve function in people with prediabetes and early diabetic neuropathy. Researchers planned to enroll 40 adults aged 55–80, but the trial was terminated early with only 31 participants. Participants took either fish oil pills or a placebo for six months, and nerve function was measured at three and six months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fish oil (n-3 polyunsaturated fatty acids)
What this could lead to
If it works, this could point toward a simple dietary supplement to help manage nerve damage from diabetes.
What could go wrong
This was a small, early trial that was terminated, so results are limited. Fish oil may not improve nerve function, and high doses can cause side effects like fishy aftertaste or digestive issues.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for DIABETIC NEUROPATHIES are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Locations
-
Washington University
St Louis, Missouri, 63110, United States
-
Washington University School of Medicine
St Louis, Missouri, 63110, United States