Can a fruit compound fight frailty in seniors?
NCT ID NCT03675724
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 2 study tests whether fisetin, a natural compound found in fruits like strawberries, can reduce inflammation and frailty in adults aged 70 and older. Forty participants will receive either fisetin or a placebo pill. The goal is to see if fisetin lowers blood markers of inflammation and improves physical function.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fisetin (a plant compound found in fruits and vegetables)
What this could lead to
If it works, this could point toward a simple supplement to help older adults feel less frail and reduce inflammation.
What could go wrong
This is a small, early-phase pilot study with only 40 participants, so results may not apply widely. The supplement may not work better than a placebo.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Mayo Clinic in Rochester
Rochester, Minnesota, 55905, United States