First patients test new pill aimed at slowing advanced cancers
NCT ID NCT03573310
Summary
This was a first-in-human study to test the safety and find the right dose of a new oral drug, JNJ-64619178, for people with advanced cancers that have not responded to other treatments. It involved 114 adults with specific advanced solid tumors, non-Hodgkin lymphoma, or a type of bone marrow disorder. The main goal was to see how much of the drug the body could tolerate and to identify a safe dose for future testing.
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Contacts and locations
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Locations
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Carmel Medical Center
Haifa, 34362, Israel
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Clinica Univ. de Navarra
Pamplona, 31008, Spain
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Florida Specialist and Cancer Institute
Sarasota, Florida, 34232, United States
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Goethe Universität Frankfurt
Frankfurt am Main, 60590, Germany
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Hadassah Medical Center
Jerusalem, 9112001, Israel
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Hosp Clinico Univ de Salamanca
Salamanca, 37007, Spain
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Hosp Univ Fund Jimenez Diaz
Madrid, 28040, Spain
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Hosp Univ Vall D Hebron
Barcelona, 08035, Spain
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Hosp. Univ. Germans Trias I Pujol
Badalona, 08916, Spain
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Hosp. Virgen Del Rocio
Seville, 41013, Spain
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Ohio State University
Columbus, Ohio, 43210, United States
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Princess Margaret Cancer Centre University Health Network
Toronto, Ontario, M5G1Z5, Canada
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St. Paul's Hospital
Vancouver, British Columbia, V6E 1M7, Canada
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Tel Aviv Sourasky MC
Tel Aviv, 6423906, Israel
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Universitaetsklinikum Duesseldorf
Düsseldorf, 40225, Germany
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Universitaetsklinikum Leipzig
Leipzig, 04103, Germany
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University of Texas, MD Anderson Cancer Center
Houston, Texas, 77030, United States
Conditions
Explore the condition pages connected to this study.