Could a heart drug help kidney patients? new trial tests finerenone for membranous nephropathy

NCT ID NCT06573411

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether adding finerenone to standard blood pressure medications can lower protein in the urine of people with primary membranous nephropathy, a kidney condition that can lead to kidney failure. About 116 adults will be randomly assigned to receive either finerenone plus standard care or standard care alone. The main goal is to see if protein levels drop more with the combination after 6 months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

finerenone

What this could lead to

If successful, this could offer a new way to reduce protein leakage in the urine for people with primary membranous nephropathy, potentially slowing kidney damage.

What could go wrong

This is a relatively small Phase 4 trial with 116 participants, and the main outcome is a lab measure (proteinuria) rather than long-term kidney health. The drug may not show meaningful benefit over standard care.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

idiopathic membranous glomerulonephritis membranous glomerulonephritis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Wei Chen

    RECRUITING

    Guangzhou, Guangdong, 510080, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••