New collagen filler aims to smooth wrinkles and scars

NCT ID NCT06336044

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new injectable filler made from hyaluronic acid and collagen to improve wrinkles, scars, and skin looseness on the face. Forty non-smoking adults aged 18-70 will receive one treatment and be followed for 16 weeks. Researchers will check for side effects and measure changes in skin appearance and hydration.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Hyaluronic acid and recombinant collagen filler (Karisma)

What this could lead to

If successful, this could offer a safe and effective option for reducing wrinkles, scars, and skin looseness.

What could go wrong

This is a small, early study with no control group. Results may not apply to all skin types or ages. Side effects like swelling or bruising are possible.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cutis laxa severe cutaneous adverse reaction

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Ospedale Tor Vergata

    RECRUITING

    Roma, 00133, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact