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Blood test could predict MS Flare-Ups, study hopes

NCT ID NCT06551519

Ongoing Knowledge-focused Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether a blood test measuring a protein called neurofilament light (sNfL) can help doctors predict and manage disease activity in people with relapsing multiple sclerosis (MS). About 489 adults with MS in Germany will be observed for 24 months. The goal is to see how often high sNfL levels occur and whether this information leads to better treatment decisions.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis relapsing-remitting multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

Contacts and locations

Locations

  • Novartis Investigative Site

    Albstadt, Baden-Wurttemberg, 72458, Germany

  • Novartis Investigative Site

    Hettingen, Baden-Wurttemberg, 72513, Germany

  • Novartis Investigative Site

    Mannheim, Baden-Wurttemberg, 68163, Germany

  • Novartis Investigative Site

    Schwetzingen, Baden-Wurttemberg, 68723, Germany

  • Novartis Investigative Site

    Bamberg, Bavaria, 96052, Germany

  • Novartis Investigative Site

    Neuburg A.d. Donau, Bavaria, 86633, Germany

  • Novartis Investigative Site

    Regensburg, Bavaria, 93059, Germany

  • Novartis Investigative Site

    Unterhaching, Bavaria, 82008, Germany

  • Novartis Investigative Site

    Untermeitingen, Bavaria, 86836, Germany

  • Novartis Investigative Site

    Weiden in Der Oberpfalz, Bavaria, 92637, Germany

  • Novartis Investigative Site

    Hamburg, Free and Hanseatic City of Hamburg, 22297, Germany

  • Novartis Investigative Site

    Frankfurt am Main, Hesse, 65929, Germany

  • Novartis Investigative Site

    Kassel, Hesse, 34121, Germany

  • Novartis Investigative Site

    Quakenbrück, Lower Saxony, 49610, Germany

  • Novartis Investigative Site

    Dortmund, North Rhine-Westphalia, 44135, Germany

  • Novartis Investigative Site

    Dortmund, North Rhine-Westphalia, 44287, Germany

  • Novartis Investigative Site

    Gelsenkirchen, North Rhine-Westphalia, 45894, Germany

  • Novartis Investigative Site

    Meerbusch, North Rhine-Westphalia, 40667, Germany

  • Novartis Investigative Site

    Siegen, North Rhine-Westphalia, 57072, Germany

  • Novartis Investigative Site

    Sundern Sauerland, North Rhine-Westphalia, 59846, Germany

  • Novartis Investigative Site

    Chemnitz, Saxony, 09117, Germany

  • Novartis Investigative Site

    Dresden, Saxony, 01307, Germany

  • Novartis Investigative Site

    Görlitz, Saxony, 02828, Germany

  • Novartis Investigative Site

    Leipzig, Saxony, 04299, Germany

  • Novartis Investigative Site

    Leipzig, Saxony, 04315, Germany

  • Novartis Investigative Site

    Altenburg, Thuringia, 04600, Germany

  • Novartis Investigative Site

    Jena, Thuringia, 07740, Germany

  • Novartis Investigative Site

    Mühlhausen, Thuringia, 99974, Germany

  • Novartis Investigative Site

    Aalen, 73433, Germany

  • Novartis Investigative Site

    Altenholz, 24161, Germany

  • Novartis Investigative Site

    Aschaffenburg, 63739, Germany

  • Novartis Investigative Site

    Augsburg, 86150, Germany

  • Novartis Investigative Site

    Backnang, 71522, Germany

  • Novartis Investigative Site

    Bad Krozingen, 79189, Germany

  • Novartis Investigative Site

    Bergneustadt, 51702, Germany

  • Novartis Investigative Site

    Berlin, 10437, Germany

  • Novartis Investigative Site

    Berlin, 12099, Germany

  • Novartis Investigative Site

    Berlin, 12163, Germany

  • Novartis Investigative Site

    Berlin, 14057, Germany

  • Novartis Investigative Site

    Berlin, 14169, Germany

  • Novartis Investigative Site

    Bielefeld, 33647, Germany

  • Novartis Investigative Site

    Bochum, 44787, Germany

  • Novartis Investigative Site

    Bogen, 94327, Germany

  • Novartis Investigative Site

    Bonn, 53111, Germany

  • Novartis Investigative Site

    Chemnitz, 09117, Germany

  • Novartis Investigative Site

    Coburg, 96450, Germany

  • Novartis Investigative Site

    Dessau, 06846, Germany

  • Novartis Investigative Site

    Dierdorf, 56269, Germany

  • Novartis Investigative Site

    Dillingen Saar, 66763, Germany

  • Novartis Investigative Site

    Dresden, 01067, Germany

  • Novartis Investigative Site

    Duisburg, 47138, Germany

  • Novartis Investigative Site

    Düsseldorf, 40211, Germany

  • Novartis Investigative Site

    Düsseldorf, 40625, Germany

  • Novartis Investigative Site

    Eisleben Lutherstadt, 06295, Germany

  • Novartis Investigative Site

    Erbach im Odenwald, 64711, Germany

  • Novartis Investigative Site

    Erfurt, 99096, Germany

  • Novartis Investigative Site

    Essen, 45138, Germany

  • Novartis Investigative Site

    Gelsenkirchen, 45879, Germany

  • Novartis Investigative Site

    Gera, 07548, Germany

  • Novartis Investigative Site

    Hagen, 58099, Germany

  • Novartis Investigative Site

    Hamburg, 22179, Germany

  • Novartis Investigative Site

    Heidenheim, 89518, Germany

  • Novartis Investigative Site

    Herford, 32049, Germany

  • Novartis Investigative Site

    Höxter, 37671, Germany

  • Novartis Investigative Site

    Itzehoe, 25524, Germany

  • Novartis Investigative Site

    Karlsruhe, 76133, Germany

  • Novartis Investigative Site

    Katzenelnbogen, 56368, Germany

  • Novartis Investigative Site

    Leipzig, 04109, Germany

  • Novartis Investigative Site

    Merzig, 66663, Germany

  • Novartis Investigative Site

    Minden, 32423, Germany

  • Novartis Investigative Site

    München, 80939, Germany

  • Novartis Investigative Site

    München, 81675, Germany

  • Novartis Investigative Site

    Münster, 48149, Germany

  • Novartis Investigative Site

    Neuwied, 56564, Germany

  • Novartis Investigative Site

    Osnabrück, 49074, Germany

  • Novartis Investigative Site

    Pforzheim, 75172, Germany

  • Novartis Investigative Site

    Remscheid, 42853, Germany

  • Novartis Investigative Site

    Rülzheim, 76761, Germany

  • Novartis Investigative Site

    Salzatal, 06198, Germany

  • Novartis Investigative Site

    Schwäbisch Hall, 74523, Germany

  • Novartis Investigative Site

    Siegen, 57076, Germany

  • Novartis Investigative Site

    Singen, 78224, Germany

  • Novartis Investigative Site

    Sinsheim, 74889, Germany

  • Novartis Investigative Site

    Stuttgart, 70174, Germany

  • Novartis Investigative Site

    Tirschenreuth, 95643, Germany

  • Novartis Investigative Site

    Ulm, 89073, Germany

  • Novartis Investigative Site

    Velbert, 42551, Germany

  • Novartis Investigative Site

    Weil der Stadt, 71263, Germany

  • Novartis Investigative Site

    Wolfenbüttel, 38300, Germany

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