Could psoriasis raise the risk of widespread pain?
NCT ID NCT07773766
First seen Aug 19, 2026 · Last updated Aug 20, 2026 · Updated 1 time
Summary
This study investigates whether adults with plaque psoriasis are more likely to have fibromyalgia and central sensitization—a condition where the nervous system becomes overly sensitive to pain—compared to healthy people. Researchers will compare 55 psoriasis patients with 55 matched healthy volunteers, using questionnaires to assess pain, fatigue, and quality of life. The goal is to understand how these conditions overlap, which could help doctors identify and manage pain in psoriasis patients earlier.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- What this could lead to
- If this study finds a strong link, it could lead to better early detection and management of chronic pain in people with psoriasis.
- What could go wrong
- This is an observational study, so it cannot prove cause and effect. The findings may not apply to all psoriasis patients, and the small sample size limits generalizability.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 110 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2026
An estimate. Start dates often move.
- Expected to finish
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Oct 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of adult male and female patients (18 years of age and older) clinically diagnosed with plaque psoriasis who are attending the Dermatology Outpatient Clinic at Assiut University Hospital. It also includes a control group of apparently healthy, age- and sex-matched volunteers.
- Ages
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18 years and older
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patients (≥18 years) with clinically diagnosed plaque psoriasis. * Both males and females. * Willing to participate and provide written informed consent. * For controls: Apparently healthy age- and sex-matched volunteers. * For controls: No history of psoriasis, psoriatic arthritis, or other chronic inflammatory or rheumatic diseases. * For controls: Willing to participate and provide written informed consent. Exclusion Criteria: * Patients with psoriatic arthritis or other inflammatory arthritis. * Patients with other diagnosed rheumatic diseases (e.g., rheumatoid arthritis, systemic lupus erythematosus, ankylosing spondylitis). * Patients with previously diagnosed major depressive disorder or generalized anxiety disorder. * Patients with uncontrolled diabetes mellitus, heart failure, renal failure, or thyroid disorders. * Current use of antidepressants, anticonvulsants, or benzodiazepines. * History of malignancy. * Pregnancy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
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