New pill could cool menopause hot flashes without hormones
NCT ID NCT06812754
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether fezolinetant, a non-hormonal drug, can reduce moderate to severe hot flashes in Chinese women going through menopause. About 150 women will take either fezolinetant or a placebo daily for 12 weeks. The goal is to see if the drug safely eases symptoms, offering an alternative to hormone therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
fezolinetant
What this could lead to
If successful, this could provide a non-hormonal treatment option for hot flashes in Chinese women going through menopause.
What could go wrong
This is a small, early-phase trial (150 participants) with a placebo control. Results may not confirm effectiveness or safety for broader use.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Beijing Hospital
Beijing, Beijing Municipality, China
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Capital Medical University (CMU) - Beijing Shijitan Hospital
Beijing, Beijing Municipality, China
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Capital Medical University - Beijing Obstetrics and Gynecology Hospital
Beijing, Beijing Municipality, China
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Chengdu Women's and Children's Central Hospital
Chengdu, Sichuan, China
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Guangxi Medical University (GXMU) - Liuzhou Renmin Hospital
Liuzhou, Guangxi, China
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Guangzhou Medical University - The Third Affiliated Hospital
Guangzhou, Guangdong, China
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Hainan Women and Children's Medical Center
Haikou, Hainan, China
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Hunan Provincial Maternal and Child Health Care Hospital
Changsha, Hunan, China
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Jiangxi Maternal and Child Health Hospital
Nanchang, Jiangxi, China
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Jilin Province FAW General Hospital
Changchun, Jilin, China
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Jinan Central Hospital Affiliated to Shandong First Medical University
Jinan, Shandong, China
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Liuzhou Worker's Hospital
Liuzhou, Guangxi, China
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Nanjing First Hospital
Nanjing, Jiangsu, China
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Peking Union Medical College Hospital
Beijing, Beijing Municipality, China
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Peking University Shenzhen Hospital
Shenzhen, Guangdong, China
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Shandong Provincial Hospital
Jinan, Shandong, China
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Shanghai First Maternity and Infant Hospital
Shanghai, Shanghai Municipality, China
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Shanxi Woman and Children Hospital
Taiyuan, Shanxi, China
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Shenzhen Maternal & Child Health Hospital
Shenzhen, Guangdong, China
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Southeast University, ZhongDa Hospital
Nanjing, Jiangsu, China
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Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University
Guangzhou, Guangdong, China
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The First hospital of Shanxi Medical University
Taiyuan, Shanxi, China
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The Second Hospital of Tianjin Medical University
Tianjin, Tianjin Municipality, China
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The second Hospital of Hebei Medical University
Shijiazhuang, Hebei, China
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Xiangya Hospital, Central South University
Zhuzhou, Hunan, China
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Zhujiang Hospital of Southern Medical University
Guangzhou, Guangdong, China