New PET scan aims to spot tiny brain tumors that standard MRI misses

NCT ID NCT07456878

Recruiting now Diagnosis Sponsor: Mayo Clinic Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early study tests a special PET/MRI scan using a radioactive tracer called FET to find small pituitary tumors that don't show up on regular MRI. The goal is to improve detection of these hormone-producing tumors in 5 adults with confirmed biochemical disease. If the scan works, it could help guide surgery and improve treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Fluoroethyl-L-tyrosine (FET)
What this could lead to: If successful, this imaging method could help doctors find hidden pituitary tumors more accurately, leading to better surgical decisions and outcomes.
What could go wrong: This is a very small, early-phase study with only 5 participants, so results may not apply widely. The scan is still experimental and its benefits over standard methods are unproven.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

acromegaly Cushing disease due to pituitary adenoma hyperprolactinemia pituitary gland adenoma Pituitary Neoplasms prolactin-producing pituitary gland adenoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PITUITARY ADENOMA

Contacts and locations

Locations

Mayo Clinic
RECRUITING

Jacksonville, Florida, 32224, United States

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