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Could a wearable nerve stimulator help MS patients walk more freely?

NCT ID NCT07706114

Not yet recruiting Symptom relief Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jul 15, 2026 · Last updated Jul 23, 2026 · Updated 3 times

Summary

This trial tests a wearable device that uses mild electrical pulses to stimulate the leg muscles of people with multiple sclerosis who have foot drop. The goal is to see if using the device for several months improves walking quality, physical activity, and participation in daily life compared to a sham device. Seventy adults with MS will be randomly assigned to receive real stimulation or a placebo for four months, then all will receive real stimulation for another four months, followed by a month without the device to check for lasting effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
functional electrical stimulation (FES) device worn on the weaker leg
What this could lead to
If effective, FES could become a standard, accessible tool to help people with MS walk better and engage more in daily life.
What could go wrong
This is a mid-sized early-stage trial (70 people) comparing FES to a sham device, so results may not apply broadly. Long-term benefits and real-world adoption remain uncertain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMPAIRED GAIT MULTIPLE SCLEROSIS

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of California San Francisco, Weill Institute for Neurosciences

    San Francisco, California, 94158, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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