New drug aims to slow kidney disease in IgA nephropathy patients

NCT ID NCT06935357

Recruiting now Disease control Sponsor: Biogen Source: ClinicalTrials.gov ↗

First seen Oct 01, 2025 · Last updated May 16, 2026 · Updated 30 times

Summary

This study tests a drug called felzartamab in people with IgA nephropathy, a kidney disease where abnormal antibodies build up and damage the kidneys. The goal is to see if felzartamab can lower the amount of protein in urine, a sign of kidney damage. About 454 adults will receive either the drug or a placebo through IV infusions over 24 weeks, followed by 80 weeks of follow-up. The study is currently recruiting.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Nantong, Jiangsu, 226001, China
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All India Institute of Medical Sciences ( AIIMS ) - Raipur
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Raipur, Chhattisgarh, 492099, India
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Brookhaven, Mississippi, 39601, United States

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Auckland City Hospital
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Auckland, 1023, New Zealand
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Reims, Grand Est, 51092, France

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Strasbourg, Bas-Rhin, 67091, France

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San Miguel de Tucumán, Tucumán Province, T4000CBC, Argentina

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Cangzhou Central Hospital
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Cangzhou, Hebei, 61011, China
Central Florida Kidney Specialists
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Orlando, Florida, 32806, United States

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La Roche-sur-Yon, Vendée, 85925, France

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Braga, 4710-243, Portugal

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Centro Mineiro de Pesquisa - CMiP
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Juiz de Fora, Minas Gerais, 36010, Brazil

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Ranica, Lombardy, 24020, Italy

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Chang Gung Memorial Hospital, Linkou
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Taoyuan, Taiwan, Province of China, 33305, Taiwan
Charité - Universitätsmedizin Berlin
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Berlin, 10117, Germany

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China Medical University Hospital - PPDS
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Taichung, Taiwan, Province of China, 40447, Taiwan
Clinica de la Costa S.A.S. - PPDS
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Barranquilla, Atlántico, 80020, Colombia
Clinical Hospital Center Rijeka
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Rijeka, 51000, Croatia

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Cliniques Universitaires Saint-Luc
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Brussels, 1200, Belgium

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Clínica de Nefrología Urología Y Enfermedades Cardiovasculares
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Santa Fe, 3000, Argentina

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Concord Repatriation General Hospital
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New South Wales, New South Wales, 2060, Australia
Consultorios Médicos Dr. Doreski - Fundacion Respirar - PPDS
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Buenos Aires, B1605, Argentina

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Buenos Aires, C1111AAH, Argentina

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Daqing Oilfield General Hospital
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Daqing, Heilongjiang, 163001, China
Elixia Health - Michigan Kidney Consultants, LLC - Elixia - PPDS
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Pontiac, Michigan, 48341, United States
Erciyes Universitesi Tip Fakultesi Gevher Nesibe Hastanesi
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Kayseri, 38039, Turkey (Türkiye)

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Far Eastern Memorial Hospital
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New Taipei City, Taiwan, Province of China, 220216, Taiwan
Freire Pesquisa Clínica
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Belo Horizonte, Minas Gerais, 30150-320, Brazil

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Fu Yang People's Hospital - South Campus
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Viladecans, Barcelona, 8840, Spain

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Fundacion Valle Del Lili
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Cali, Valle del Cauca Department, 760032, Colombia
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Gold Coast University Hospital
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Government Medical College, Kozhikode
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Kozhikode, Kerala, 673008, India
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Southport, Queensland, 4222, Australia
Hallym University Sacred Heart Hospital
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Hamamatsu, Sizouka, 431-3192, Japan
Hanyang University Seoul Hospital
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Seoul, Seoul Teugbyeolsi, 4763, South Korea
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Henry Ford Hospital
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Hirosaki University Hospital
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Perak, Pahang, 30450, Malaysia
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Kitakyushu-shi, Hukuoka, 807-8556, Japan
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Rozzano, Lombardy, 20089, Italy

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Ikeda Municipal Hospital
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Ikeda-shi, Ôsaka, 563-8510, Japan
Inje University Haeundae Paik Hospital
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Busan, 48108, South Korea
Institut klinicke a experimentalni mediciny
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Prague, Praha, Hlavní Mesto, 140 21, Czechia

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Belo Horizonte, Minas Gerais, 30150221, Brazil

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Istanbul, 34098, Turkey (Türkiye)

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James J Peters Veterans Administration Medical Center - NAVREF - PPDS
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The Bronx, New York, 10468, United States

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Ieper, West-Vlaanderen, 8900, Belgium

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Jiading Central Hospital
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Shanghai, Shanghai Municipality, 201899, China
Jikei University Hospital
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Minato-ku, Tokyo, 105-8471, Japan
Jinhua Municipal Central Hospital
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Jinhua, Zhejiang, 321000, China
John Hunter Hospital
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New Lambton, New South Wales, 2305, Australia
Juntendo University Hospital
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Bunkyo-Ku, Tokyo, 113-8431, Japan
Juntendo University Urayasu Hospital
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Urayasu-Shi, Chiba, 279-0021, Japan
Kaohsiung Medical University - Chung-Ho Memorial Hospital
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Kaohsiung City, 807, Taiwan
Kawasaki Medical School Hospital
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Kurashiki, Okayama-ken, 701-0192, Japan
Kidney & Hypertension Center - Apple Valley
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Apple Valley, California, 92307, United States

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King George Medical University
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Lucknow, Uttar Pradesh, 226003, India
Kitasato University Hospital
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Sagamihara-shi, Kanagawa, 252-0375, Japan
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Zagreb, City of Zagreb, 10000, Croatia

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Knoxville Kidney Center, PLLC
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Knoxville, Tennessee, 37923-3624, United States

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İzmit, Kocaeli, 41380, Turkey (Türkiye)

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Athens, Attica, 11527, Greece

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Leicester, Leicestershire, LE5 4PW, United Kingdom

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Providence, Rhode Island, 02903, United States

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Bangalore, Karnataka, 560054, India
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Krakow, Lesser Poland Voivodeship, 30727, Poland

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Mackay Memorial Hospital-Taipei branch
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Taipei, Taiwan, Province of China, 104449, Taiwan
Maffei Centro Médico
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Buenos Aires, C1425, Argentina

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Manipal Hospital Bangalore
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Bangalore, Karnataka, 560017, India
Marmara Universitesi Pendik Egitim ve Arastirma Hastanesi
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Istanbul, Turkey, 34899, Turkey (Türkiye)

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Max Super Speciality Hospital - Saket
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New Delhi, National Capital Territory of Delhi, 110017, India
McGill University Health Centre (MUHC)
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Montreal, Quebec, H4A3J1, Canada

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Montana, 3400, Bulgaria

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Medical Center Medconsult Pleven - Lovech Branch
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Lovech, 5500, Bulgaria

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Medical Center Medconsult Pleven OOD
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Pleven, 5800, Bulgaria

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Mehmet Akif Inan Egitim ve Arastirma Hastanesi
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Sanliurfa, Turkey, 63040, Turkey (Türkiye)

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Midwest Nephrology Associates,Inc.
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City of Saint Peters, Missouri, 63376, United States
Muljibhai Patel Society for Research in Nephro-Urology
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Nadiād, Gujarat, 387001, India
Nara Medical University Hospital
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Kashihara, Nara, 634-8522, Japan
National Cheng Kung University Hospital
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Dawan, Taiwan, Province of China, 70403, Taiwan
National Hospital Organization Chiba Medical Center Chibahigashi National Hospital
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Chiba, Chiba, 260-8712, Japan
National Institute of clinical Research Administration Office
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Garden Grove, California, 92844-2751, United States
Nephrologisches Zentrum Villingen-Schwenningen
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Villingen-Schwenningen, Baden-Wurttemberg, 78052, Germany

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Nil Ratan Sircar Medical College and Hospital
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Kolkata, West Bengal, 700014, India
Nizams Institute of Medical Sciences
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Hyderabad, Andhra Pradesh, 500082, India
Noble Hospital
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Pune, Maharashtra, 411013, India
North America Research Institute-San Dimas
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San Dimas, California, 91773, United States

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Norzel Medical and Diagnostic Clinic Foundation Corp.
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Cebu City, Cebu, 6000, Philippines
Nova Clinical Research, LLC
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Bradenton, Florida, 34209, United States

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Osaka University Hospital
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Suita-shi, Ôsaka, 565-0871, Japan
Osmania General Hospital
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Hyderabad, Andhra Pradesh, 500012, India
PAGNI-University General Hospital of Heraklion
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Heraklion, Irakleio, 715 00, Greece

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Peking University First Hospital - Changqiao Campus
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Beijing, Beijing Municipality, 100034, China
Peking University Shenzhen Hospital
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Shenzhen, Guangdong, 518036, China
Penn Renal Electrolyte and Hypertension Perelman
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Philadelphia, Pennsylvania, 19104, United States

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Polyclinic Bonifarm
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Zagreb, City of Zagreb, 10000, Croatia

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Postgraduate Institute of Medical Education & Research (PGIMER)
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Chandigarh, 160012, India
Provecta Research Network
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Houston, Texas, 77054, United States

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Pusan National University Hospital
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Busan, Gwangyeogsi, 49241, South Korea
Qilu Hospital of Shandong University
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Jinan, Shandong, 250012, China
R & H Clinical Research
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Katy, Texas, 77974, United States

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Royal Preston Hospital - NWCRN- PPDS
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Preston, Lancashire, PR2 9HT, United Kingdom

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Royal Research, Corp.
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Hollywood, Florida, 33024, United States

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Royal Stoke University Hospital
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Stoke-on-Trent, Staffordshire, ST4 6QG, United Kingdom

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SCM Clinic - Prywatny Szpital Specjalistyczny
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Krakow, Lesser Poland Voivodeship, 31-559, Poland

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SPZOZ Centralny Szpital Kliniczny UM w Lodzi - ul. Pomorska 251
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Lodz, Lódzkie, 92-213, Poland

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Samsung Medical Center
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Seoul, 6351, South Korea
Sanjay Gandhi Postgraduate Institute of Medical Sciences
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Lucknow, Uttar Pradesh, 226014, India
Scripps Green Hospital
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Carlsbad, California, 92009, United States

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Seoul National University Bundang Hospital
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Seongnam-si, Gyeonggido, 13620, South Korea
Seoul National University Hospital
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Seoul, 03080, South Korea
Seth G S Medical College and K E M Hospital
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Mumbai, Maharashtra, 400012, India
Severance Hospital Yonsei University Health System
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Seoul, Seoul Teugbyeolsi, 3722, South Korea
Shanghai General Hospital - North Campus
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Shanghai, Shanghai Municipality, 200080, China
Shenzhen Hospital of Southern Medical University
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Shenzhen, Guangdong, 510086, China
Showa Medical University Hospital
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Shinagawa-ku, Tokyo, 142-86666, Japan
Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital
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Chengdu, Sichuan, 610072, China
Sir Ganga Ram Hospital
RECRUITING

New Delhi, National Capital Territory of Delhi, 110060, India
Special Hospital Medico
RECRUITING

Rijeka, 51000, Croatia

Contact Phone: •••-•••-••••

Contact
St Paul's Hospital
NOT_YET_RECRUITING

Vancouver, British Columbia, V6Z 1Y6, Canada

Contact Phone: •••-•••-••••

Contact
Sunshine Hospital - Australia
NOT_YET_RECRUITING

St Albans, Victoria, 3021, Australia
Taipei Medical University Shuang Ho Hospital
RECRUITING

New Taipei City, 235041, Taiwan
Taipei Municipal Wanfang Hospital
RECRUITING

Taipei, Taiwan, Province of China, 116081, Taiwan
Taizhou Hospital of Zhejiang Province - Main
RECRUITING

Taizhou, Zhejiang, 317000, China
Texas Kidney Institute - Dallas
RECRUITING

Dallas, Texas, 95231, United States

Contact Phone: •••-•••-••••

Contact
The Affiliated Hospital of Guizhou Medical University
RECRUITING

Guiyang, Guizhou, 550000, China
The First Affiliated Hospital of Anhui Medical University - Jixilu Campus
RECRUITING

Hefei, Anhui, 230022, China
The First Affiliated Hospital of Guangxi Medical University
RECRUITING

Nanning, Guangxi, 530021, China
The First Affiliated Hospital of Guangzhou Medical University - Yanjiang Campus
RECRUITING

Guangzhou, Guangdong, 510120, China
The First Affiliated Hospital of Henan Science and Technology University - Jinghua Campus
RECRUITING

Luoyang, Henan, 471003, China
The Jikei University West Medical Center
RECRUITING

Ashikaga-Shi, Tokyo, 326-0843, Japan
The People's Hospital of Guangxi Zhuang Autonomous Region
RECRUITING

Nanning, Guangxi, 530021, China
The Second Affiliated Hospital of Nanjing Medical University
RECRUITING

Nanjing, Jiangsu, 210011, China
The Second Hospital of Hebei Medical University - Main
RECRUITING

Shijiazhuang, Hebei, 50000, China
The Second Hospital of Shandong University
RECRUITING

Jinan, Shandong, 250033, China
The Third Hospital of Hebei Medical University
RECRUITING

Shijiazhuang, Hebei, 50000, China
The Vasculitis and Glomerulonephritis Center at Massachusetts General Hospital
RECRUITING

Boston, Massachusetts, 02114-4724, United States

Contact Phone: •••-•••-••••

Contact
Tohoku Medical and Pharmaceutical University Hospital
RECRUITING

Sendai, Miyagi, 983-8512, Japan
Tokushima University Hospital
RECRUITING

Tokushima, Tokushima, 770-8503, Japan
Toranomon Hospital Kajigaya
RECRUITING

Kawasaki-shi, Kanagawa, 213-0015, Japan
Townsville Hospital
RECRUITING

Douglas, Queensland, 4814, Australia
Trivandrum Medical College Hospital
NOT_YET_RECRUITING

Trivandrum, Kerala, 695011, India
Twoja Przychodnia - Szczecinskie Centrum Medyczne
RECRUITING

Szczecin, West Pomeranian Voivodeship, 71-434, Poland

Contact Phone: •••-•••-••••

Contact
ULS da Arrábida, EPE - Hospital de São Bernardo
RECRUITING

Setúbal, 2910-446, Portugal

Contact Phone: •••-•••-••••

Contact
ULS da Região de Aveiro, EPE - Hospital Infante D. Pedro
RECRUITING

Aveiro, 3814, Portugal

Contact Phone: •••-•••-••••

Contact
ULS da Região de Leiria, EPE - Hospital de Santo André
RECRUITING

Leiria, 2410-197, Portugal

Contact Phone: •••-•••-••••

Contact
ULS de Coimbra, EPE - Hospitais da Universidade de Coimbra
RECRUITING

Coimbra, 3004-561, Portugal

Contact Phone: •••-•••-••••

Contact
ULS de Gaia/Espinho, EPE - Unidade I
RECRUITING

Vila Nova de Gaia, Lisbon District, 4434-502, Portugal

Contact Phone: •••-•••-••••

Contact
ULS de Lisboa Ocidental, EPE - Hospital Santa Cruz
RECRUITING

Carnaxide, Lisbon District, 2790, Portugal

Contact Phone: •••-•••-••••

Contact
UMass Memorial Medical Center
NOT_YET_RECRUITING

Worcester, Massachusetts, 01655, United States

Contact Phone: •••-•••-••••

Contact
UZ Leuven - PPDS
RECRUITING

Leuven, Vlaams Brabant, 3000, Belgium

Contact Phone: •••-•••-••••

Contact
University General Hospital ''ATTIKON'' - General Hospital of West Attica H AGIA VARVARA
RECRUITING

Chaïdári, Attica, 12462, Greece

Contact Phone: •••-•••-••••

Contact
University General Hospital of Ioannina
RECRUITING

Ioannina, 34098, Greece

Contact Phone: •••-•••-••••

Contact
University General Hospital of Patras
RECRUITING

Pátrai, Achaïa, 26500, Greece

Contact Phone: •••-•••-••••

Contact
University Hospital, Kyoto Prefectural University of Medicine
RECRUITING

Kyoto, Kyôto, 602-8566, Japan
University Malaya Medical Centre
RECRUITING

Lembah Pantai, WilayahPersekutuan KualaLumpur, 59100, Malaysia
University Multiprofile Hospital for Active Treatment Sv Ivan Rilski EAD-15 Acad. Ivan Geshov Blvd
RECRUITING

Sofia, 1606, Bulgaria

Contact Phone: •••-•••-••••

Contact
University of Florida - Gainesville - 1600 SW Archer Rd
NOT_YET_RECRUITING

Gainesville, Florida, 32610, United States

Contact Phone: •••-•••-••••

Contact
Universitätsklinikum Carl Gustav Carus an der TU Dresden
RECRUITING

Dresden, Saxony, 1307, Germany

Contact Phone: •••-•••-••••

Contact
Universitätsklinikum Frankfurt, Apotheke Haus 19
RECRUITING

Frankfurt am Main, Hesse, 60596, Germany

Contact Phone: •••-•••-••••

Contact
Universitätsmedizin der Johannes Gutenberg-Universität Mainz
RECRUITING

Mainz, Rhineland-Palatinate, 55131, Germany

Contact Phone: •••-•••-••••

Contact
Uniwersytecki Szpital Kliniczny Nr 2 PUM w Szczecinie
RECRUITING

Szczecin, 70-110, Poland

Contact Phone: •••-•••-••••

Contact
Uniwersyteckie Centrum Kliniczne w Gdansku - Debinki 7
RECRUITING

Gdansk, Pomeranian Voivodeship, 80-952, Poland

Contact Phone: •••-•••-••••

Contact
Wellington Hospital
NOT_YET_RECRUITING

Wellington, 6021, New Zealand
Westmead Hospital
RECRUITING

Westmead, New South Wales, 2145, Australia
Wuxi Peoples Hospital
RECRUITING

Wuxi, Jiangsu, 214023, China
Yantai Yuhuangding Hospital
NOT_YET_RECRUITING

Yantai, Shandong, 264000, China
Yichang Central People's Hospital - Wujiagang Campus
RECRUITING

Yichang, Hubei, 443003, China
Yokohama City University Hospital
RECRUITING

Yokohama, Kanagawa, 236-0004, Japan
ZOL Genk - campus Sint-Jan
NOT_YET_RECRUITING

Genk, Limburg, 3600, Belgium

Contact Phone: •••-•••-••••

Contact
Zhongshan Hospital Xiamen University
RECRUITING

Xiamen, Fujian, 361004, China
Zhongshan Hospital of Traditional Chinese Medicine
RECRUITING

Zhongshan, Guangdong, 528401, China
Zydus Hospital
RECRUITING

Ahmedabad, Gujarat, 380081, India

Conditions

Explore the condition pages connected to this study.

IMMUNOGLOBULIN A NEPHROPATHY (IGAN)