Placebo power: fake TENS and kind words may ease MS fatigue
NCT ID NCT07624812
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed pilot study looked at whether a placebo treatment — sham TENS combined with positive verbal suggestions — could reduce fatigue in people with relapsing-remitting multiple sclerosis. 36 participants were enrolled. The main goal was to measure motor performance (number of flexions) and brain activity (Readiness Potential) to see if fatigue could be modulated without real therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sham TENS therapy combined with positive verbal suggestions
What this could lead to
If it works, this could point toward a non-drug way to help MS patients manage fatigue.
What could go wrong
This is a very small pilot study with only 36 people, testing a placebo effect. Results may not apply to real-world treatment.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ospedale San Giuseppe
Piancavallo, Verbanio-Cusio-Ossola, 28824, Italy