Placebo power: fake TENS and kind words may ease MS fatigue
NCT ID NCT07624812
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed pilot study looked at whether a placebo treatment — sham TENS combined with positive verbal suggestions — could reduce fatigue in people with relapsing-remitting multiple sclerosis. 36 participants were enrolled. The main goal was to measure motor performance (number of flexions) and brain activity (Readiness Potential) to see if fatigue could be modulated without real therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- sham TENS therapy combined with positive verbal suggestions
- What this could lead to
- If it works, this could point toward a non-drug way to help MS patients manage fatigue.
- What could go wrong
- This is a very small pilot study with only 36 people, testing a placebo effect. Results may not apply to real-world treatment.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Ospedale San Giuseppe
Piancavallo, Verbanio-Cusio-Ossola, 28824, Italy
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Other studies related to the condition(s) this trial covers.
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