Can tired muscles change how you feel pain?

NCT ID NCT07577622

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how different levels of fatigue from leg strength exercises affect pain perception in healthy adults. 27 participants will do three sessions of leg extensions with varying fatigue levels. Researchers will measure pain sensitivity, strength, and perceived effort to understand the link between exercise fatigue and pain relief.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Strength training (leg extension machine)
What this could lead to
If successful, this could help design better exercise programs for pain management.
What could go wrong
This is a small, early-stage study in healthy volunteers, so results may not apply to people with chronic pain. The effect on pain is temporary and not a treatment.

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Conditions

The condition(s) this trial relates to.

Fatigue Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Universidad Miguel Hernández

    Alicante, ALICANTE, 03550, Spain

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