Fat graft may keep Dupuytren's disease from returning after surgery

NCT ID NCT05067764

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

Dupuytren's disease causes fingers to bend inward, making hand use difficult. This study compares standard surgery (aponeurectomy) alone versus surgery plus a fat graft taken from the patient's arm. Researchers will track 172 adults for 2 years to see if the fat graft reduces the chance of the disease coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

adipose tissue (fat) graft

What this could lead to

If it works, this could offer a simple way to reduce the chance of Dupuytren's coming back after surgery, helping people keep hand function longer.

What could go wrong

This is a relatively small, early-stage trial. The fat graft may not lower recurrence rates, and there are risks like infection or graft failure. Results may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

palmar fibromatosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Institut Aquitain de la Main

    RECRUITING

    Pessac, 33600, France

    Contact Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Santé Atlantique ELSAN

    RECRUITING

    Saint-Herblain, 44800, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••