Fat graft may keep Dupuytren's disease from returning after surgery

NCT ID NCT05067764

Recruiting now Disease control Sponsor: Elsan Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

Dupuytren's disease causes fingers to bend inward, making hand use difficult. This study compares standard surgery (aponeurectomy) alone versus surgery plus a fat graft taken from the patient's arm. Researchers will track 172 adults for 2 years to see if the fat graft reduces the chance of the disease coming back.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: adipose tissue (fat) graft
What this could lead to: If it works, this could offer a simple way to reduce the chance of Dupuytren's coming back after surgery, helping people keep hand function longer.
What could go wrong: This is a relatively small, early-stage trial. The fat graft may not lower recurrence rates, and there are risks like infection or graft failure. Results may not apply to everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

palmar fibromatosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DUPUYTREN'S DISEASE

Contacts and locations

Locations

Institut Aquitain de la Main
RECRUITING

Pessac, 33600, France
Santé Atlantique ELSAN
RECRUITING

Saint-Herblain, 44800, France

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