New drug trial aims to control inherited polyp condition that leads to colon cancer

NCT ID NCT06557733

Summary

This study is testing whether an oral medication called TPST-1495 can reduce the number of polyps in the small intestine and rectum of people with familial adenomatous polyposis (FAP), an inherited condition that causes many polyps and increases colon cancer risk. The trial will enroll 38 adults who have already had their colon removed as a preventive measure. Participants will take the medication daily for 6 months while researchers measure changes in polyp growth and monitor safety.

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Contacts and locations

Locations

  • Huntsman Cancer Institute/University of Utah

    Salt Lake City, Utah, 84112, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Mayo Clinic Hospital in Arizona

    Phoenix, Arizona, 85054, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • Mayo Clinic in Rochester

    Rochester, Minnesota, 55905, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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  • University of Wisconsin Carbone Cancer Center - University Hospital

    Madison, Wisconsin, 53792, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

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Conditions

Explore the condition pages connected to this study.