Scientists track rare family condition to uncover hidden clues about blood disorder

NCT ID NCT00091871

First seen Jun 25, 2026 · Last updated Aug 05, 2026 · Updated 10 times

Summary

This study follows about 50 members of a family with a rare inherited condition called familial hypereosinophilia, where high levels of a type of white blood cell can damage the heart and nerves. Researchers will track participants over many years with yearly checkups, blood tests, and heart and lung tests to understand how the condition develops and what causes it. The goal is to find genetic markers and early signs of disease progression, which could lead to better monitoring and future treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to
If successful, this study could reveal genetic causes and early warning signs of familial hypereosinophilia, pointing toward better monitoring or future treatments.
What could go wrong
This is an observational study with only 50 participants from one family, so findings may not apply to others. It does not test any treatment, so no direct benefit is guaranteed.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for EOSINOPHILIA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    RECRUITING

    Bethesda, Maryland, 20892, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.