Scientists track rare family condition to uncover hidden clues about blood disorder
NCT ID NCT00091871
First seen Jun 25, 2026 · Last updated Aug 05, 2026 · Updated 10 times
Summary
This study follows about 50 members of a family with a rare inherited condition called familial hypereosinophilia, where high levels of a type of white blood cell can damage the heart and nerves. Researchers will track participants over many years with yearly checkups, blood tests, and heart and lung tests to understand how the condition develops and what causes it. The goal is to find genetic markers and early signs of disease progression, which could lead to better monitoring and future treatments.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could reveal genetic causes and early warning signs of familial hypereosinophilia, pointing toward better monitoring or future treatments.
- What could go wrong
- This is an observational study with only 50 participants from one family, so findings may not apply to others. It does not test any treatment, so no direct benefit is guaranteed.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
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