HYPEREOSINOPHILIC SYNDROME
Clinical trials for HYPEREOSINOPHILIC SYNDROME explained in plain language.
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New hope for rare blood disorder: dupilumab combo shows promise
Disease control Recruiting nowThis study tests whether adding dupilumab to current treatments can help adults with hypereosinophilic syndrome (HES) who still have symptoms. HES causes too many eosinophils, damaging organs like lungs and skin. Participants will receive dupilumab injections for up to 48 weeks w…
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Phase: PHASE2 • Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Disease control
Last updated May 14, 2026 12:05 UTC
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New hope for rare blood disorder: drug cuts dangerous flares
Disease control Recruiting nowThis study tests an investigational drug called depemokimab in adults with hypereosinophilic syndrome (HES) that is not well controlled by current treatments. About 123 participants will receive either depemokimab or a placebo, added to their usual therapy, for 52 weeks. The main…
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Phase: PHASE3 • Sponsor: GlaxoSmithKline • Aim: Disease control
Last updated May 11, 2026 20:49 UTC
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New hope for rare blood disorder: ruxolitinib trial targets eosinophils
Disease control Recruiting nowThis study tests the drug ruxolitinib in 10 people with hypereosinophilic syndrome or related disorders, where high levels of eosinophils (a type of white blood cell) cause organ damage. The goal is to see if ruxolitinib can lower eosinophil counts and improve symptoms. Participa…
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Phase: PHASE2 • Sponsor: William Shomali • Aim: Disease control
Last updated Apr 29, 2026 15:05 UTC
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600 patients join national effort to unravel mysteries of rare blood disorder
Knowledge-focused Recruiting nowThis study is collecting information from 600 people with chronic high eosinophil levels (hypereosinophilia) or hypereosinophilic syndrome. Researchers want to understand the different symptoms, organ problems, and disease patterns over time. They will also look at genetic and en…
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Sponsor: University Hospital, Lille • Aim: Knowledge-focused
Last updated May 12, 2026 13:42 UTC
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Scientists track rare blood disorder in families to unlock its secrets
Knowledge-focused Recruiting nowThis study follows about 50 family members who have a genetic condition causing high levels of a type of white blood cell (eosinophils), which can damage organs like the heart and nerves. Researchers will track participants over many years with yearly check-ups, blood tests, and …
Matched conditions: HYPEREOSINOPHILIC SYNDROME
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated May 04, 2026 16:23 UTC