Hidden genetic disorder found in chronic pain patients?

NCT ID NCT02450604

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested 776 people with chronic pain of unknown cause to see if they had Fabry disease, a rare inherited disorder that can cause pain, kidney, heart, and nerve problems. Researchers used enzyme tests in men and genetic tests in women to find cases. The goal was to see how common Fabry disease is in this group and help diagnose it earlier.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors identify Fabry disease earlier in people with unexplained chronic pain, leading to better management.

What could go wrong

This is an observational study, not a treatment trial. It only looks for the disease and does not test any therapy, so it cannot directly improve outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Chronic Pain chronic pain syndrome Fabry disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Anesthésie, Hôpital Raymond Poincaré

    Garches, 92380, France

  • CETD La Timone, AP-HM

    Marseille, 13385, France

  • CeRCa, Unité de Neuromyologie, CHU de Fort de France

    FORT de France, Martinique, 97261, France

  • Centre Antidouleurs, CHU de Reims

    Reims, 51092, France

  • Centre Douleurs Chroniques, CH de la Côte Basque

    Bayonne, 64109, France

  • Centre Douleurs Chroniques, CHU de Bordeaux

    Bordeaux, 33076, France

  • Centre d'Analgésie Pédiatrique, Equipe Régionale Ressource en Soins Palliatifs-Equipe " Enfant-Do ", CHU de Toulouse

    Toulouse, 31059, France

  • Centre d'Analgésie, CHRU Lapeyronie

    Montpellier, 34295, France

  • Centre d'Evaluation et de Traitement de la Douleur, CHU de Nîmes

    Nîmes, 30029, France

  • Centre d'évaluation et de traitement de la Douleur, Hôpital Pierre-Paul Ricquet

    Toulouse, 31059, France

  • Centre de la Douleur, CHRU de Strasbourg

    Strasbourg, 67091, France

  • Centre de la douleur de l'Adulte et de l'Enfant, CHU de Grenoble

    Grenoble, 38043, France

  • Cs douleur chronique GHSR, CHU Sud Réunion

    Saint-Pierre, La Réunion, 97448, France

  • Médecine - Consultations Douleur, CH de La Réole

    La Réole, 33192, France

  • Pole enfant - CETD Salengro, CHRU de Lille

    Lille, 59037, France

  • Pôle Anesthésie Consultation douleur, CHRU de Lille

    Lille, 59037, France

  • Service d'Explorations Fonctionnelles et Consultations Neurologiques, CH Lyon-Sud

    Pierre-Bénite, 69495, France

  • Service de Médecine de la Douleur et de Médecine Palliative, Hôpital Lariboisière-APHP

    Paris, 75475, France

  • Service de lutte contre la douleur et d'Anesthésie, CH Périgueux

    Périgueux, 24 019, France

  • Service de médecine Polyvalent, CH de La Dracénie

    Draguignan, 83007, France

  • Unité Douleur et Soins Palliatifs, CH La Rochelle-Réaunis

    La Rochelle, 17019, France