New scan could sharpen liver cancer detection

NCT ID NCT07019844

Recruiting now Diagnosis Sponsor: VA Office of Research and Development Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether adding a special PET scan (using F18-Piflufolastat) to standard imaging can better diagnose and stage liver cancer. Researchers will enroll 90 veterans with suspected or confirmed hepatocellular carcinoma. The goal is to see if the scan helps clarify uncertain liver spots, improve staging, and assess treatment response more accurately.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: F18-Piflufolastat (a radioactive tracer for PET/CT imaging)
What this could lead to: If successful, this imaging method could help doctors more accurately diagnose and stage liver cancer, leading to better treatment choices.
What could go wrong: This is a small, early-stage study (90 participants) at a single center. The tracer may not improve accuracy enough to change patient outcomes, and results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

hepatocellular carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HEPATOCELLULAR CARCINOMA (HCC)

Contacts and locations

Locations

Miami VA Healthcare System, Miami, FL
RECRUITING

Miami, Florida, 33125, United States
VA Greater Los Angeles Healthcare System, West Los Angeles, CA
RECRUITING

West Los Angeles, California, 90073-1003, United States

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