New combo aims to reboot immune attack on tough lung cancers

NCT ID NCT05467748

First seen Nov 01, 2025 · Last updated Apr 29, 2026 · Updated 23 times

Summary

This study tests whether adding an experimental drug (tulmimetostat) to an existing immunotherapy (pembrolizumab) can shrink tumors or slow cancer growth in people with advanced non-small cell lung cancer whose disease has worsened after initial treatments. About 66 veterans will receive the combination therapy. The goal is to see if the drugs are safe and effective at controlling the cancer, not to cure it.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for NON SMALL CELL LUNG CANCER are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Michael E. DeBakey VA Medical Center, Houston, TX

    RECRUITING

    Houston, Texas, 77030-4211, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • VA Ann Arbor Healthcare System, Ann Arbor, MI

    RECRUITING

    Ann Arbor, Michigan, 48105-2303, United States

    Contact Email: •••••@•••••

  • VA Long Beach Healthcare System, Long Beach, CA

    NOT_YET_RECRUITING

    Long Beach, California, 90822, United States

    Contact Email: •••••@•••••

  • VA Northern California Health Care System, Mather, CA

    NOT_YET_RECRUITING

    Sacramento, California, 95655-4200, United States

    Contact Email: •••••@•••••

  • VA San Diego Healthcare System, San Diego, CA

    RECRUITING

    San Diego, California, 92161-0002, United States

    Contact Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.