Eye test may predict who benefits from depression therapy

NCT ID NCT07474974

First seen Jun 27, 2026 · Last updated Aug 07, 2026 · Updated 2 times

Summary

This study looks at whether a simple eye test can predict how well people with treatment-resistant depression will respond to a brain stimulation therapy called TMS. Researchers will measure how the pupils react to light before and after TMS treatment in 44 adults. The goal is to find a way to personalize depression care and avoid ineffective treatments.

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Conditions

The condition(s) this trial relates to.

Depressive Disorder, Treatment-Resistant major depressive disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • RISE-Health, Center for Translational Health and Medical Biotechnology Research (TBIO), School of Health, Polytechnic of Porto

    RECRUITING

    Porto, Porto District, 4200-072, Portugal

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