Cure My Disease

Don't miss your cure!

 Log in / Sign up

ACL recovery pill trial pulled before it began

NCT ID NCT07115056

Symptom relief Sponsor: Campbell Clinic Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled This study
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study planned to test whether taking tranexamic acid pills for 10 days after ACL knee surgery could reduce pain and improve recovery in 100 teens and young adults. However, the trial was withdrawn before enrolling anyone, so no results are available.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
tranexamic acid (TXA)
What this could lead to
If it had worked, this could have pointed toward a simple, cheap way to reduce pain and speed up recovery after ACL surgery.
What could go wrong
The trial was withdrawn before it started, so we have no results. Even if it had run, it was a small, early-phase study that might not have shown clear benefits or been generalizable to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Phase 4

Runs after approval, following long-term safety and how well the treatment works in everyday use.

Expected to start

Apr 2026

An estimate. Start dates often move.

Expected to finish

Dec 2029

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

14 to 22 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * 14-22 year old individuals with ACL tear undergoing primary ACLR with patellar tendon autograft. * Closed or closing proximal tibial and distal femoral physes on pre-operative radiographs (less than one year of growth remaining based on MRI and radiographic bone age assessment) * Fluent in English * Willing to participate * Patient weight greater than or equal to 100lbs (45.4kg) Exclusion Criteria: * Revision ACLR, multi-ligamentous knee reconstruction, inclusion of lateral extra-articular tenodesis (LET) or Anterolateral Ligament (ALL) reconstruction * Concomitant meniscal repair or chondral preservation surgery requiring postoperative limited weightbearing status (nonweightbearing or partial weightbearing) * Have a prior history of deep vein thrombosis (DVT) or thromboembolic event * Known allergy or hypersensitivity to TXA * Using combination hormonal contraception

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for Acl injury are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

Anterior Cruciate Ligament Injuries

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Acl injury Acl surgery Acl tears

Contacts and locations

Locations

  • Campbell Clinic

    Germantown, Tennessee, 38138, United States

  • Duke University School of Medicine

    Durham, North Carolina, 27705, United States

  • Endeavor Health

    Evanston, Illinois, 60201, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45221, United States

  • University of Pittsburgh

    Pittsburgh, Pennsylvania, 15260, United States

  • Washington University School of Medicine in St. Louis

    Chesterfield, Missouri, 63017, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.