Could a simple antibiotic pill after surgery save diabetic patients from infection?

NCT ID NCT07561541

Recruiting now Disease control Sponsor: Texas Tech University Health Sciences Center, El Paso Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study is testing whether taking an antibiotic pill for 7 days after surgery to fix a broken leg, ankle, or foot can lower the chance of wound infection in adults with poorly controlled diabetes. About 40 participants will either receive the antibiotic or standard care (no extra antibiotics). Researchers will track infections and side effects for 90 days after surgery.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Cefadroxil (or Clindamycin or Bactrim DS as alternatives)
What this could lead to: If it works, this could point toward a simple way to prevent wound infections after fracture surgery in people with diabetes.
What could go wrong: This is a small pilot study with only 40 participants, so results may not apply broadly. Antibiotics can cause side effects like stomach upset or allergic reactions.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

bone fracture diabetes mellitus

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DIABETES FRACTURE FIXATION, INTERNAL FRACTURE LOWER LEG

Contacts and locations

Locations

Texas Tech Health El Paso
RECRUITING

El Paso, Texas, 79912, United States
University Medical Center of El Paso
RECRUITING

El Paso, Texas, 79905, United States
University of Southern California
RECRUITING

Los Angeles, California, 90033, United States

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