New scoring tool could predict when ventilator patients can breathe on their own

NCT ID NCT05085457

Completed Diagnosis Sponsor: Universidade do Oeste de Santa Catarina Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new scoring system called ExPreS to help doctors decide when patients on breathing machines (ventilators) are ready to have the tube removed. Over 500 adults in intensive care units were randomly assigned to use ExPreS or standard care. The goal was to see if ExPreS could improve the number of successful extubations and reduce the need to put the tube back in.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: ExPreS diagnostic scoring protocol
What this could lead to: If successful, this scoring tool could help doctors more accurately decide when to remove a breathing tube, reducing complications and time in the ICU.
What could go wrong: This is a completed trial, but the score may not work for all patient types or in all hospitals. The study is relatively small and results may not apply broadly.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

respiratory failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

RESPIRATORY INSUFFICIENCY

Contacts and locations

Locations

Hospital Universitário Santa Terezinha

Joaçaba, Santa Catarina, 89600-000, Brazil

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