Can stem cell 'Messages' heal blood vessels after preeclampsia?

NCT ID NCT07183384

Recruiting now Disease control Sponsor: Universitas Padjadjaran Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether tiny particles from stem cells, called exosomes, can repair blood vessel damage in women who had preeclampsia during pregnancy. Preeclampsia raises the risk of heart disease later in life, and current treatments don't fully heal the blood vessels. The trial will involve 80 postpartum women, half receiving the exosome treatment and half a placebo, with follow-up after one week to check blood vessel health.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Mesenchymal stem cell-derived exosomes (MSC-Exos)
What this could lead to: If it works, this could lead to a treatment that repairs blood vessel damage after preeclampsia, potentially lowering the risk of heart disease later in life.
What could go wrong: This is an early phase 1/2 trial with only 80 participants, so results may not apply to all women. The treatment is new, and side effects or lack of benefit are possible.

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Conditions

The condition(s) this trial relates to.

preeclampsia puerperal disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CELL THERAPY ENDOTHELIAL INJURY EXOSOME MULTIOMICS POSTPARTUM PREECLAMPSIA

Contacts and locations

Locations

Dr. Hasan Sadikin Central General Hospital
RECRUITING

Bandung, West Java, 40161, Indonesia

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