Exercise as medicine: new trial tests workouts for heart condition

NCT ID NCT05818605

Recruiting now Symptom relief Sponsor: University of California, San Francisco Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether 24 weeks of moderate exercise (three 60-minute sessions per week) can improve symptoms and heart function in people with hypertrophic cardiomyopathy, a condition where the heart muscle is thickened. About 70 participants will be randomly assigned to either the exercise program or their usual activity. Researchers will measure changes in exercise capacity, heart strain, and other markers.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Moderate Intensity Exercise Program
What this could lead to: If it works, this could show that structured exercise safely improves exercise capacity and quality of life for people with hypertrophic cardiomyopathy.
What could go wrong: This is a small, early-stage trial with only 70 participants. Exercise may not improve heart function, and some patients might experience discomfort or risks from increased activity.

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Conditions

The condition(s) this trial relates to.

hypertrophic cardiomyopathy

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

HYPERTROPHIC CARDIOMYOPATHY

Contacts and locations

Locations

University of California - San Francisco
RECRUITING

San Francisco, California, 94143, United States

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