Wheelchair users with MS may gain strength and mobility through tailored exercise

NCT ID NCT06410261

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 13, 2026 · Last updated Jul 14, 2026 · Updated 1 time

Summary

This study tests whether a 6-month personalized exercise program can improve physical and cognitive function in people with multiple sclerosis (MS) who primarily use a wheelchair. Participants will follow a low-impact, resistance-based routine designed to build muscle without increasing fatigue or pain. The goal is to see if this approach can boost strength, walking ability, and daily function.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
exercise rehabilitation program (GH method)
What this could lead to
If successful, this program could offer a way to improve muscle strength, walking ability, and reduce fatigue for wheelchair users with MS.
What could go wrong
This is a small pilot study with only 24 participants, so results may not apply to everyone. The program requires commitment and may not work for all individuals.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 24 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2024

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * diagnosis of MS * age above 18 years * no relapse within last 30 days * use of wheelchair for mobility in the community * ability to walk at least 50 feet (or 65 steps) using an assistive device * low risk for contraindications of physical activity indicated by no more than a single "yes" * response on the Physical Activity Readiness Questionnaire (PAR-Q) * willingness to complete the assessments and undergo randomization Exclusion Criteria: * no diagnosis of MS * less than 18 years of age * not relapse-free within the last 30 days * no use of wheelchair as primary mobility device * no ability to walk for at least 50 feet (or 65 steps) * high risk for contraindications based on more than a single "yes" response on the PAR-Q * not willing to complete the testing procedures and undergo randomization

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Conditions

The condition(s) this trial relates to.

Motor Activity multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • University of Illinois at Chicago

    RECRUITING

    Chicago, Illinois, 60612, United States

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