Exercise explored as a tool against muscle loss in liver disease
NCT ID NCT05982769
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at how 12 weeks of endurance or resistance exercise affects muscle loss and ammonia buildup in people with cirrhosis. Cirrhosis can cause the liver to fail at processing ammonia, leading to muscle wasting and confusion. Researchers will compare two types of home-based exercise to standard care in 40 adults. The goal is to understand the molecular mechanisms behind exercise benefits in cirrhosis.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Exercise (endurance training and resistance training)
What this could lead to
If successful, this could help establish specific exercise guidelines for cirrhosis patients to prevent muscle loss and improve quality of life.
What could go wrong
This is a small, early-stage study (40 participants) focused on understanding mechanisms, not proving a treatment. Results may not apply to all cirrhosis patients.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Cleveland Clinic
RECRUITINGCleveland, Ohio, 44195, United States
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