Centenarians put to the test: can exercise reverse frailty at age 100?
NCT ID NCT07723339
First seen Jul 23, 2026 · Last updated Jul 24, 2026 · Updated 1 time
Summary
This trial tests whether a home-based exercise program tailored to people aged 100 and older can improve physical function, balance, and quality of life. Participants will follow a personalized routine of strength, balance, and aerobic exercises with regular check-ins. The study aims to see if even at very advanced ages, targeted movement can make a meaningful difference.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- an individualized multicomponent physical exercise program including strength, balance, flexibility, and mobility training
- What this could lead to
- If it works, this could point toward a practical way to preserve mobility and independence in the oldest old.
- What could go wrong
- The trial is small (60 participants) and limited to relatively healthy centenarians, so results may not apply to frailer individuals. Exercise carries a low risk of falls or injury.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Navarrabiomed
Pamplona, Navarre, 31001, Spain
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