Exercise may boost Well-Being in advanced colorectal cancer patients
NCT ID NCT06938971
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at whether a structured 18-week exercise program can improve health-related quality of life in people with metastatic colorectal cancer who are starting their first round of chemotherapy. About 150 adults will be randomly assigned to either the exercise group or a control group. The goal is to see if exercise helps them feel better physically and emotionally during treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 150 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2025
- Expected to finish
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May 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: \- Adults (≥18 years of age) schduled to undergo first-line chemotherapy for the treatment of metastatic colorectal cancer. Exclusion criteria : * Pregnancy. * A life expectancy of \< 6 months. * Absolute contraindications to maximal exercise, as per the recommendations by the Danish Society of Cardiology. * ECOG (Eastern Cooperative Oncology Group) performance status \> 2. * Inability to understand the Danish or English language. * Engagement in structured moderate-to-high aerobic exercise training for \>30 min \>1 times/week for the past 3 months at the time of inclusion.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
4 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Centre for Physical Activity Research, Copenhagen Univerisity Hospital - Rigshospitalet
RECRUITINGCopenhagen, 2100, Denmark
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Herlev and Gentofte Hospital
RECRUITINGHerlev, 2730, Denmark
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North Zealand University Hospital, Hillerød
RECRUITINGHillerød, 3400, Denmark
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Zealand University Hospital, Roskilde
RECRUITINGRoskilde, 4000, Denmark
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Other studies related to the condition(s) this trial covers.
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