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Exercise your brain: new study tests fitness program for cognitive decline

NCT ID NCT06799429

Symptom relief Sponsor: University of South Carolina Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests a twice-weekly, moderate-intensity exercise and coaching program for adults with mild-moderate cognitive impairment. Researchers want to see if the program is practical and enjoyable, and whether it can improve endurance, mobility, and thinking over 12 months. The study includes both in-person and remote groups, with 50 participants from South Carolina.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
supervised exercise and behavior modification support
What this could lead to
If it works, this could point toward a practical, non-drug way to help people with cognitive impairment maintain or improve their physical and mental function.
What could go wrong
This is a small, early-stage feasibility study with only 50 participants, so results may not apply to everyone. The program requires regular attendance and may be hard to stick with long-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 50 people

The number the study aims to enrol. It can still change while the study runs.

Started

Mar 2026

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion criteria: * adult (age \>18) * medical diagnosis of mild-moderate cognitive impairment * medical clearance by referring provider for exercise * able to follow 2-step commands Exclusion criteria: * significant pain with movement (\>5/10) * severe balance impairments or lack of independence on and off exercise equipment (by physical therapist judgment at Intake)

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cognitive impairment Mild-moderate cognitive impairment

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    2 sites. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Arnold School of Public Health

    RECRUITING

    Columbia, South Carolina, 29208, United States

  • Sumter YMCA

    RECRUITING

    Sumter, South Carolina, 29150, United States

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