Exercise may sharpen aging minds in HIV patients

NCT ID NCT06013579

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether high-intensity interval training (HIIT) or moderate continuous exercise can improve thinking, memory, and daily function in 110 older adults with HIV who are sedentary and fatigued. Participants will exercise three times a week for four months. The goal is to see if exercise can lower dementia risk and help build long-term exercise habits.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

high-intensity interval training (HIIT) and continuous moderate exercise (CME)

What this could lead to

If successful, this could show that structured exercise programs help preserve brain function and build lasting exercise habits in older adults with HIV.

What could go wrong

This is a small, early-stage study (110 participants) without a placebo control, so results may not apply broadly. Exercise adherence and individual health differences could affect outcomes.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction HIV infectious disease Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alabama at Birmingham

    NOT_YET_RECRUITING

    Birmingham, Alabama, 35294, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Colorado Denver

    RECRUITING

    Aurora, Colorado, 80045, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • University of Washington

    RECRUITING

    Seattle, Washington, 98195, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••