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Could a workout during dialysis sharpen the mind?

NCT ID NCT07780175

Symptom relief Sponsor: University of Thessaly Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing This study
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Aug 21, 2026 · Last updated Aug 21, 2026

Summary

This trial tests whether exercise done during dialysis sessions can help people with end-stage kidney disease think more clearly and feel better day-to-day. Participants will be randomly assigned to standard care alone or to one of three exercise programs—aerobic, resistance, or a combination—performed while receiving hemodialysis. Researchers will measure changes in cognitive function and quality of life over six months to see if any exercise type offers benefits.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Exercise training during dialysis (aerobic, resistance, or combined)
What this could lead to
If effective, this could establish exercise during dialysis as a way to improve thinking, mental health, and daily life for kidney patients.
What could go wrong
The trial is small and early, and results may not apply to all patients. Some may find exercise during dialysis challenging or unsafe.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

60 people

The number who actually took part.

Started

Jul 2026

Expected to finish

Jul 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Able to provide written informed consent. * Chronic kidney disease stage 5 / end-stage kidney disease. * Established on maintenance hemodialysis for at least 3 months. Exclusion Criteria: * Newly established on hemodialysis for less than 3 months. * Terminal illness with life expectancy shorter than the 6-month intervention/follow-up period. * Clinically unstable condition as determined by the treating clinical team. * Diagnosis of dementia, Alzheimer disease, or severe cognitive dysfunction, defined as a Mini-Mental State Examination score below 17 points. * Pregnancy at baseline or at any point during the intervention. * Physical complication or limitation that prevents safe participation in exercise training.

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Conditions

The condition(s) this trial relates to.

chronic kidney disease end stage renal failure

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Clinical exercise Exercise adaptations Exercise training therapy Supportive care

Contacts and locations

Locations

  • School of Life and Health Sciences

    Nicosia, Nicosia, CY1700, Cyprus

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