Exercise plus fish oil shows promise for MS fatigue and strength

NCT ID NCT07346703

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study will test whether taking a daily DHA (omega-3) supplement and doing therapeutic exercise three times a week can improve strength, fatigue, thinking, and quality of life in 100 people with multiple sclerosis. Participants will be randomly assigned to one of four groups: DHA alone, DHA plus exercise, placebo (sunflower oil) alone, or placebo plus exercise. The goal is to see if the combination works better than either approach alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
docosahexaenoic acid (DHA) dietary supplement
What this could lead to
If it works, this could point toward a simple, non-drug way to help manage fatigue and improve physical function in people with multiple sclerosis.
What could go wrong
This is a small, early-stage study with no blinding for exercise, so results may be influenced by placebo effects or participant expectations. DHA supplements are generally safe but may cause mild digestive issues.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Center for High Performance Sport. Universidad Católica de Murcia

    La Ñora, Murcia, 30830, Spain

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