Exercise study reveals how workout intensity may control appetite hormones

NCT ID NCT04581980

First seen Oct 31, 2025 · Last updated Jun 22, 2026 · Updated 31 times

Summary

This study looked at how different exercise intensities change levels of ghrelin, a hormone that controls hunger, in 40 adults with obesity and prediabetes. Participants exercised on a stationary bike, and researchers measured ghrelin, appetite, and blood vessel function. The goal was to understand how exercise might influence metabolism and cardiovascular health in this group.

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Contacts and locations

Locations

  • University of Virginia

    Charlottesville, Virginia, 22902, United States

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exercise (cycling)

What this could lead to

If successful, this could help explain how exercise affects appetite and metabolism, potentially guiding future weight management strategies.

What could go wrong

This is a small, completed observational study with only 40 participants. Results may not apply to everyone, and it does not test a treatment or cure.

Conditions

The condition(s) this trial relates to.

Insulin Resistance Motor Activity Obesity obesity disorder prediabetes syndrome

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.