Exercise plus brain zaps may boost memory in At-Risk seniors

NCT ID NCT05079464

Recruiting now Symptom relief Sponsor: Sunnybrook Health Sciences Centre Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether exercising before a mild brain stimulation session can improve memory in people with mild cognitive impairment linked to heart or blood vessel problems. 64 adults aged 50 and older will be randomly assigned to receive either real or sham brain stimulation, with or without exercise. The goal is to see if priming the brain with exercise makes the stimulation work better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial direct current stimulation (tDCS) and exercise
What this could lead to: If it works, this could point toward a non-drug way to boost memory in people with early cognitive decline.
What could go wrong: This is a small, early-phase study (64 people) testing a combination approach. Results may not apply to everyone, and the effect may be small or temporary.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Motor Activity vascular dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MILD COGNITIVE IMPAIRMENT VASCULAR COGNITIVE IMPAIRMENT

Contacts and locations

Locations

Sunnybrook Health Sciences Centre
RECRUITING

Toronto, Ontario, M4N 3M5, Canada

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