Exercise plus brain zaps may boost memory in At-Risk seniors

NCT ID NCT05079464

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether exercising before a mild brain stimulation session can improve memory in people with mild cognitive impairment linked to heart or blood vessel problems. 64 adults aged 50 and older will be randomly assigned to receive either real or sham brain stimulation, with or without exercise. The goal is to see if priming the brain with exercise makes the stimulation work better.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial direct current stimulation (tDCS) and exercise

What this could lead to

If it works, this could point toward a non-drug way to boost memory in people with early cognitive decline.

What could go wrong

This is a small, early-phase study (64 people) testing a combination approach. Results may not apply to everyone, and the effect may be small or temporary.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Cognitive Dysfunction Motor Activity vascular dementia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Sunnybrook Health Sciences Centre

    RECRUITING

    Toronto, Ontario, M4N 3M5, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••