Blood test could reveal hidden cancer spread in colorectal patients

NCT ID NCT07224724

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

The EXELION study is testing a new blood test that looks for tiny particles called exosomal microRNAs to find out if colorectal cancer has spread beyond the liver. Current scans often miss small or hidden metastases, which can affect treatment options. The study will enroll 500 adults with metastatic colorectal cancer to see how accurate this liquid biopsy is compared to standard imaging.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

exosomal microRNA panel measured in blood

What this could lead to

If successful, this blood test could help doctors find small cancer spread that scans miss, leading to better treatment choices and possibly more patients eligible for surgery.

What could go wrong

This is an early-stage study focused on developing and testing the test's accuracy. It may not prove better than current imaging, and the test is not yet available for routine use.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

colorectal cancer colorectal neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • City of Hope Medical Center

    RECRUITING

    Duarte, California, 91010, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••