Blood test could reveal hidden cancer spread in colorectal patients
NCT ID NCT07224724
First seen Jun 25, 2026 · Last updated Jul 08, 2026 · Updated 3 times
Summary
The EXELION study is testing a new blood test that looks for tiny particles called exosomal microRNAs to find out if colorectal cancer has spread beyond the liver. Current scans often miss small or hidden metastases, which can affect treatment options. The study will enroll 500 adults with metastatic colorectal cancer to see how accurate this liquid biopsy is compared to standard imaging.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- exosomal microRNA panel measured in blood
- What this could lead to
- If successful, this blood test could help doctors find small cancer spread that scans miss, leading to better treatment choices and possibly more patients eligible for surgery.
- What could go wrong
- This is an early-stage study focused on developing and testing the test's accuracy. It may not prove better than current imaging, and the test is not yet available for routine use.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
City of Hope Medical Center
RECRUITINGDuarte, California, 91010, United States
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Other studies related to the condition(s) this trial covers.
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- AI model aims to predict liver metastasis after colon cancer surgery