Scientists Fine-Tune Clot-Busting drug for brain hemorrhage in the lab

NCT ID NCT07411079

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study uses blood samples from over 1,100 people to create artificial clots in the lab, mimicking brain hemorrhages. Researchers test a modified clot-busting drug (rtPA) to find the best dose for different bleeding risks. The goal is to improve clot removal and guide future treatments for this serious condition.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

modified tissue plasminogen activator (rtPA)

What this could lead to

If successful, this could lead to personalized dosing of clot-busting drugs for brain hemorrhage patients, potentially improving clot removal and reducing disability.

What could go wrong

This is an early lab study using artificial clots, not real patients. Results may not translate to actual treatment, and the drug's safety and effectiveness in people remain unproven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

hemorrhagic disease intracerebral hemorrhage Intracranial Hemorrhages vascular hemostatic disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • CHU de Lille

    RECRUITING

    Lille, 59000, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••